Trehalose-6-phosphate Phosphatase fromMycobacterium tuberculosisinduces humoral and cellular immune responses
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An HIV-1 Mini Vaccine Induced Long-lived Cellular and Humoral Immune Responses
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متن کاملInteractions among sites responsible for trehalose 6-phosphate and trehalose-activated glucose 6-phosphate hydrolysis on trehalose phosphatase isolated from Phormia regina.
An enzyme capable of carrying out a trehalose-activated hydrolysis of glucose 6-phosphate has been purified 86-fold from whole body extracts of Phormia regina. By means of a number of criteria, it has been shown that the same enzyme is capable of activity against trehalose-6-P, although hydrolysis of the latter substrate is not activated by trehalose. It appears that the hydrolytic sites are ov...
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Preparations of the trehalose-6-phosphate synthase/phosphatase complex from Saccharomyces cerevisiae contain three polypeptides with molecular masses 56, 100 and 130 kDa, respectively. Recently, we have cloned the gene for the 56-kDa subunit of this complex (TPS1) and found it to be identical with CIF1, a gene essential for growth on glucose and for the activity of trehalose-6-phosphate synthas...
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Q fever is a zoonosis caused by the intracellular bacterium Coxiella burnetii. Both humoral and cellular immunity are important in the host defence against intracellular bacteria. Little is known about the immune response to C. burnetii infections in domestic ruminants even though these species are the major source of Q fever in humans. To investigate the goat's immune response we inoculated gr...
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ژورنال
عنوان ژورنال: FEMS Immunology & Medical Microbiology
سال: 2007
ISSN: 0928-8244,1574-695X
DOI: 10.1111/j.1574-695x.2006.00174.x